Peptides

Cyclotetrapeptide-24 Aminocyclohexane Carboxylate

INCI: CYCLOTETRAPEPTIDE-24 AMINOCYCLOHEXANE CARBOXYLATE

Reviewed by Rosie · Last updated 14 Aug 2026

Also known as: Cyclotetrapeptide-24 Aminocyclohexane Carboxylate

A peptide-based antioxidant designed to help protect skin from environmental stress

Best For Skin Types

All

Addresses

Environmental stress, Oxidative damage, Skin resilience

Usage Frequency

Daily

What Is Cyclotetrapeptide-24 Aminocyclohexane Carboxylate?

Cyclotetrapeptide-24 Aminocyclohexane Carboxylate is a synthetic peptide—a short chain of amino acids—formulated with an aminocyclohexane carboxylate structure. Peptides are thought to have a role in supporting skin function, and this particular ingredient is primarily used for its antioxidant properties.

Antioxidants work by neutralising free radicals, unstable molecules that form in response to environmental stressors like UV exposure and pollution. By reducing free radical damage, antioxidants aim to help maintain skin integrity and support overall skin health.

Benefits for Your Skin

How It Works

The ingredient functions as an antioxidant by donating electrons to neutralise free radicals before they can damage skin cells and collagen. This is a foundational mechanism in antioxidant chemistry and is thought to help reduce oxidative stress in the skin.

The peptide structure may also allow it to interact with skin cells in ways that support barrier function and cellular health, though the specific cellular pathways for this ingredient remain less well-characterised in published literature.

Clinical Evidence & References

Published clinical research specifically investigating this ingredient is limited. Much of what we know about its effects comes from in vitro and theoretical understanding of how peptide-based antioxidants behave in skin formulations.

General antioxidant efficacy in skincare is well-established, and peptides have shown promise in supporting skin barrier function in other contexts. However, to understand the specific efficacy of this ingredient at typical use concentrations, more human trials would be valuable.

How to Use

This ingredient is most effective when used as part of a broader skincare routine that includes sun protection, as it works best when environmental stress is minimised from the outset. It can typically be incorporated into serums or lightweight moisturisers and used consistently over time. Like most antioxidants, it pairs well with other supportive ingredients but doesn't require special sequencing.

Safety & Precautions

Generally well-tolerated in skincare formulations. As with any new ingredient, perform a patch test if you have sensitive skin or a history of reactions to peptide-based products.

Frequently Asked Questions

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