Brightening Agents

Glycyrrhiza Glabra Root Extract

INCI: GLYCYRRHIZA GLABRA ROOT EXTRACT

Reviewed by Emma · Last updated 14 Aug 2026

Also known as: Glycyrrhiza Glabra (Licorice) Root Extract

A plant extract traditionally used to address uneven skin tone and soothe irritation

Best For Skin Types

All, Sensitive, Combination

Addresses

Hyperpigmentation, Redness, Sensitivity, Barrier repair

Usage Frequency

Daily

What Is Glycyrrhiza Glabra Root Extract?

Glycyrrhiza glabra root extract, commonly known as liquorice extract, is derived from the roots of the liquorice plant. It contains several bioactive compounds, including glabridin and liquiritin, which have been studied for their effects on skin pigmentation and inflammation.

In skincare formulations, this ingredient functions as a skin conditioner and soothing agent. It appears in roughly 3% of commercial skincare products, often at concentrations that vary widely depending on the intended use and formulation type.

How It Works

The depigmenting effects of liquorice extract appear to work through multiple pathways. Research indicates that glabridin, one of its key active compounds, may inhibit melanin production by affecting the CRTC1/MITF signalling pathway—a crucial mechanism in how skin cells regulate pigment formation.

The soothing and anti-inflammatory effects are thought to stem from the extract's broader phytochemical profile, though the precise mechanisms are not yet fully mapped. This multi-action approach means the ingredient may offer benefits across several skin concerns simultaneously, though individual response can vary.

Clinical Evidence & References

Available research supports the traditional use of liquorice extract for addressing hyperpigmentation. Studies using isolated fractions—particularly those enriched with glabridin—have demonstrated depigmenting activity in laboratory and in vitro settings. However, most clinical evidence comes from controlled research environments rather than large-scale human trials, so real-world efficacy in skincare products may differ depending on concentration, formulation, and individual skin characteristics.

Evidence for its soothing and barrier-supportive properties is more limited in peer-reviewed literature, though these uses are well-established in traditional medicine. The ingredient appears to be well-tolerated in cosmetic formulations, though more research on optimal concentrations and long-term use would help clarify its full potential.

How to Use

Liquorice extract is typically found in serums, essences, moisturisers, and treatment masks. Since it functions well as part of a broader skincare routine, it can be layered with other active ingredients. If you are targeting hyperpigmentation, consistent use over several weeks is generally recommended, as effects on skin tone are gradual. There is no evidence that it requires cycling or rest periods.

Safety & Precautions

Liquorice extract is generally well-tolerated and considered safe for topical use in cosmetic products. Those with known sensitivity to liquorice or related plants should perform a patch test before widespread use.

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