Hydroxymethoxyphenyl Decanone
Reviewed by Emma · Last updated 18 Aug 2026
Also known as: Ginger Extract
Synthetic molecule analog to natural antioxidant paradol | Provides antioxidant benefits
Addresses
EWG Safety Score
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What Is Hydroxymethoxyphenyl Decanone?
Hydroxymethoxyphenyl decanone is a synthetic skin care ingredient that’s analog to paradol, an antioxidant often found in Aframomum melegueta (grains of paradise) and Zingiber officinale (ginger).
Hydroxymethoxyphenyl decanone exhibits anti-aging benefits related to its antioxidant properties. Through the mitigation of damage that external aggressors can cause, it helps to reduce the appearance of fine lines, wrinkles and dark spots. In research conducted ex vivo (outside the body), hydroxymethoxyphenyl decanone also helped stimulate the production of natural moisturizing factor hyaluronic acid.
Beyond its antioxidant benefits, this ingredient also soothes skin through the inhibition of mediators that can contribute to redness and other signs of irritation on skin.
When formulated in an ingredient blend with bisabolol, the blend is recommended for usage in concentrations between 0.05 and 0.2%.
The CIR Expert Panel has not yet reviewed this ingredient; however, based on what we know now, it has a good safety profile when used as directed.
Clinical Evidence & References
Published Research
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UL Prospector, Accessed February 2023, Webpage [https://www.ulprospector.com/en/na/PersonalCare/Detail/3030/738684/SymDecanox-HA]
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Journal of Drugs in Dermatology, April 2020, pages 398-404 [https://jddonline.com/articles/developing-a-topical-adjunct-to-injectable-procedures-S1545961620P0398X/?_page=5]
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