Addresses
EWG Safety Score
What Is Oligopeptide-76?
Oligopeptide-76 is a synthetic peptide comprised of 13 amino acids - alanine, aspartic acid, glutamic acid, glycine, isoleucine, leucine, lysine, phenylalanine, and serine. While there isn’t an extensive amount of research on oligopeptide-76’s performance in skin care products, what does exist is very interesting. In addition to the usual skin barrier improvement that most peptides provide, there is evidence suggesting that oligopeptide-76 has antimicrobial properties, including against Cutibacterium acnes, the organism whose pathogenic strains are chiefly responsible for acne breakouts. Oligopeptide-76 is also known by its trade name, SpecPed® O76P. The recommended use level of oligopeptide-76 in cosmetics is 0.001-0.1%, a testament to its potency.
Clinical Evidence & References
Published Research
-
Covalo, Website, Accessed November 2025 [https://covalo.com/]
-
Biologics, May 2025, pages 1-17 [https://www.mdpi.com/2673-8449/5/2/15]
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
Oligopeptide-51
A peptide ingredient that supports skin conditioning and structural integrity
Oligopeptide-6
A peptide fragment that conditions and supports skin's structural integrity
Oligopeptide-68
A peptide that works to reduce tyrosinase activity and address uneven skin tone
Oligopeptide-78
A peptide fragment that supports skin conditioning and structural integrity
Oligopeptide-79
A peptide ingredient used primarily to condition and support hair fibre resilience
Oligopeptide-8
A peptide fragment with purifying properties to help maintain skin clarity
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.