Oligopeptide-99 Amide

Oligopeptide-99 Amide is a synthetic peptide—a short chain of amino acids—designed to offer multiple skincare functions. Peptides are small enough to penetrate the outer layers of skin, making them useful ingredients for targeted benefits.This ingredient is classified as an antimicrobial, antioxidant, and skin-protecting agent. It is also noted for antiseborrhoeic properties, meaning it may help regulate sebum production. These functions work together to support skin health and resilience.

As a peptide, Oligopeptide-99 Amide works through multiple pathways. Its antimicrobial properties help reduce bacterial colonisation, whilst its antioxidant function neutralises reactive oxygen species (free radicals) that accumulate from environmental stressors like pollution and UV exposure.The antiseborrhoeic activity suggests it may interact with sebaceous gland function to help regulate oil production. Together, these mechanisms support the skin's natural defences and help maintain barrier function.

Oligopeptide-99 Amide is typically found in serums, moisturisers, and targeted treatments. It pairs well with other antioxidants and barrier-supporting ingredients. For best results, use consistently as part of your daily routine, and combine with broad-spectrum sunscreen to maximise protection against environmental stressors.

Peptides are generally well-tolerated by most skin types. As with any new ingredient, introduce gradually and discontinue if irritation occurs. Those with known peptide sensitivities should patch-test first.