Peptides

Palmitoyl Ascorbyl Glucoside

INCI: PALMITOYL ASCORBYL GLUCOSIDE

Reviewed by Rosie · Last updated 14 Aug 2026

Also known as: Palmitoyl Ascorbyl Glucoside

A stable vitamin C derivative that brightens and hydrates without the instability of pure ascorbic acid

Best For Skin Types

All, Oily, Combination, Dry, Mature

Addresses

Hyperpigmentation, Dull skin tone, Fine lines

Usage Frequency

Daily

What Is Palmitoyl Ascorbyl Glucoside?

Palmitoyl ascorbyl glucoside is a derivative of vitamin C (ascorbic acid) that has been chemically modified to improve stability and skin penetration. The molecule consists of ascorbic acid bonded to a palmitic acid chain and a glucose molecule, which together make it more shelf-stable than pure vitamin C whilst allowing it to work on the skin.

As well as its antioxidant properties, this ingredient also functions as a humectant and emulsifier in formulations, meaning it helps draw moisture into the skin and keep products evenly mixed.

Benefits for Your Skin

How It Works

Once applied to the skin, palmitoyl ascorbyl glucoside is broken down by skin enzymes to release free ascorbic acid (vitamin C). This process is slower than with some other vitamin C forms, which may result in gentler, more sustained activity on the skin.

Vitamin C works as an antioxidant by neutralising free radicals and supporting collagen synthesis. The humectant properties help the skin's moisture barrier function by drawing water into the outer layers.

Clinical Evidence & References

Research on palmitoyl ascorbyl glucoside specifically is limited compared to other vitamin C derivatives. Studies suggest it can deliver vitamin C benefits to skin, though its efficacy may depend on formulation pH, concentration, and the presence of other ingredients that support skin penetration.

Evidence indicates that vitamin C derivatives generally support skin brightening and antioxidant protection, though the extent varies between different forms. More targeted clinical studies on this particular derivative would help establish its comparative effectiveness.

How to Use

Apply to clean, dry skin in the morning or evening, or incorporate into your existing routine. Since this ingredient is more stable than ascorbic acid, it does not require special storage conditions. Allow the product to dry fully before applying other layers. Vitamin C products work well alongside sunscreen during the day and can be combined with other actives such as niacinamide or hyaluronic acid.

Safety & Precautions

Generally well-tolerated across most skin types. As with any vitamin C product, patch test first if you have sensitive skin, as some users may experience mild irritation or dryness when starting out.

Frequently Asked Questions

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