Palmitoyl Tetrapeptide-95

Palmitoyl Tetrapeptide-95 is a synthetic peptide—a short chain of amino acids attached to a fatty acid (palmitic acid). Peptides are often used in skincare to signal skin cells to maintain or improve structural proteins, particularly collagen and elastin, which naturally decline with age.This particular peptide is primarily used in eye creams and targeted anti-ageing formulations, where it aims to address the delicate periorbital region's specific needs: hydration, elasticity and firmness.

Palmitoyl Tetrapeptide-95 functions as a signalling molecule. The peptide portion communicates with skin fibroblasts (the cells responsible for producing collagen and elastin), whilst the attached fatty acid helps it penetrate the skin barrier more effectively.By stimulating these cells, the ingredient may encourage the maintenance and production of extracellular matrix proteins, helping to preserve or improve skin firmness and elasticity over time. This is particularly useful in areas prone to dehydration and loss of elasticity, such as around the eyes.

This ingredient is typically found in eye creams and should be applied to clean skin around the orbital area using a gentle patting motion with your ring finger. Use morning and evening as part of your skincare routine. Results tend to develop gradually over several weeks of consistent use, so patience is important.

Palmitoyl Tetrapeptide-95 is generally well-tolerated and suitable for sensitive skin formulations. No significant safety concerns have been documented, though as with any new ingredient, patch test if you have particularly reactive skin.