Peptides

Palmitoyl Tripeptide-1

INCI: pal-GHK

Reviewed by Emma · Last updated 18 Aug 2026

Also known as: palmitoyl oligopeptide

Collagen-boosting peptide for firmer skin

Addresses

ageing, wrinkles, loss of firmness, fine lines

What Is Palmitoyl Tripeptide-1?

Palmitoyl Tripeptide-1 is a synthetic peptide that mimics the body's natural mechanism for stimulating collagen production. It acts as a signal peptide, communicating with fibroblasts to increase synthesis of collagen, elastin, and glycosaminoglycans.

Often combined with Palmitoyl Tetrapeptide-7 in the trademarked complex Matrixyl 3000, this peptide has demonstrated significant anti-wrinkle effects in clinical studies. The palmitoyl group enhances skin penetration.

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Other forms of Palmitoyl Tripeptide-1

These appear on ingredients lists under different names but are the same substance. Palmitoyl Tripeptide-1 is the common form.

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