Palmitoyl Tripeptide-37

Palmitoyl Tripeptide-37 is a synthetic peptide — a short chain of amino acids with a palmitoyl (fatty acid) group attached to its structure. This modification allows the ingredient to penetrate the skin more effectively and interact with skin cells at a deeper level.In formulations, it functions primarily as a skin conditioning agent, working to support the skin's natural processes and help maintain a healthy skin barrier. It is used in a range of facial care products, typically at modest concentrations.

Peptides like Palmitoyl Tripeptide-37 work by signalling to skin cells, potentially stimulating natural processes involved in maintaining skin structure and function. The palmitoyl fatty acid component helps the peptide penetrate the skin more efficiently, allowing it to reach viable skin cells where it can exert its effects.The precise cellular mechanisms are still being explored in research, but peptides are believed to interact with receptors on skin cells in ways that may support collagen production and skin barrier integrity.

This ingredient is typically found in serums, moisturisers and targeted treatments. As with other peptide-based products, consistent use over several weeks is likely necessary to observe any potential benefits. It can generally be incorporated into both morning and evening routines without issue.

Peptides are generally well-tolerated across skin types. However, those prone to fungal acne should note that some peptides can potentially feed malassezia; patch testing is advisable if you have this concern.