Pentapeptide-28

Pentapeptide-28 is a short chain peptide—a molecule composed of five amino acids linked together. Peptides are fragments of proteins, and in skincare they function as signalling molecules that communicate with skin cells to support various biological processes.In formulations, pentapeptide-28 is primarily used as a skin conditioning agent. Its role is to help maintain skin hydration and support the skin's natural moisture barrier, contributing to a smoother, more supple appearance.

Peptides like pentapeptide-28 work by signalling to skin cells, encouraging them to maintain optimal hydration and support structural proteins. As a conditioning agent, it helps seal moisture into the outer layers of the skin and may reinforce the skin barrier's ability to retain water.The peptide's small molecular size allows it to penetrate the outer layers of skin more readily than larger protein molecules, potentially allowing it to interact with cells more effectively.

Pentapeptide-28 is typically found in serums, moisturisers, and creams. Use it as part of your regular skincare routine, applying it to clean skin before heavier moisturisers. It can be used daily, morning and evening, and layers well with other skincare ingredients. There is no need to use it in isolation; it complements other conditioning and hydrating ingredients effectively.

Peptides are generally well-tolerated and considered low-risk ingredients in skincare. Pentapeptide-28 is unlikely to cause irritation for most skin types, though those with very sensitive skin may wish to patch-test first.