Peptides

Sh-Decapeptide-7

INCI: SH-DECAPEPTIDE-7

Reviewed by Rosie · Last updated 14 Aug 2026

A peptide with antioxidant and protective properties for ageing and stressed skin

Best For Skin Types

All, Mature, Sensitive

Addresses

Fine lines, Oxidative stress, Barrier repair, Sensitivity

Usage Frequency

Daily

What Is Sh-Decapeptide-7?

Sh-Decapeptide-7 is a synthetic peptide—a short chain of amino acids designed to mimic natural skin-conditioning compounds. Peptides are used in skincare because they can interact with skin cells and support various protective functions.

This ingredient functions primarily as an antioxidant and skin protectant. It also has chelating properties, meaning it can bind to metal ions that may otherwise trigger oxidative damage, and buffering capacity to help stabilise pH in formulations.

Benefits for Your Skin

How It Works

As we age, the skin experiences cumulative damage from external factors such as sun exposure, which generates free radicals—unstable molecules that degrade collagen and impair skin structure. Antioxidants like Sh-Decapeptide-7 neutralise these free radicals before they can cause harm.

Additionally, the peptide's chelating function removes trace metals from the skin microenvironment, reducing their potential to catalyse oxidative stress. This dual mechanism helps protect the skin's natural defences and supports its ability to maintain barrier function and tissue resilience.

Clinical Evidence & References

Research confirms that oxidative stress and loss of dermal collagen are central to skin aging. Peptide-based ingredients are recognised as a category with antioxidant and skin-protective potential; however, specific clinical data on Sh-Decapeptide-7 is limited in publicly available literature.

The ingredient's inclusion in skincare formulations is based on its chemical properties and established peptide science, though individual efficacy studies would be needed to quantify its impact on wrinkles, elasticity, or barrier function in human skin.

How to Use

Sh-Decapeptide-7 is typically found in serums, moisturisers, and protective creams formulated for mature or environmentally stressed skin. Apply to clean skin morning and evening as part of your routine. It works well layered with other antioxidants and hydrating ingredients, and poses no known compatibility issues with common skincare actives.

Safety & Precautions

Sh-Decapeptide-7 is generally well-tolerated and not known to cause irritation or sensitisation. As with any new ingredient, conduct a patch test if you have highly sensitive skin.

Frequently Asked Questions

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