Sh-Heptapeptide-18

Sh-Heptapeptide-18 is a synthetic peptide—a short chain of amino acids—designed to mimic natural skin-protective mechanisms. Peptides are commonly used in skincare because they can be small enough to penetrate the skin barrier, where they may interact with skin cells to support various functions.This particular peptide is classified as an antioxidant and skin protectant, meaning it may help defend skin against environmental stressors and support the skin's natural defence systems. It is also noted for antiseborrhoeic properties, suggesting a potential role in managing excess sebum production.

Peptides like Sh-Heptapeptide-18 work by signalling to skin cells. Once absorbed, they can interact with receptors on the skin's surface and within deeper layers, potentially triggering cells to reinforce the skin barrier, produce protective compounds, or regulate sebum output.The antioxidant component of this peptide helps protect skin from oxidative stress—a process triggered by sun exposure, pollution, and other environmental factors. By reducing oxidative damage, it may help slow the visible signs of ageing, such as fine lines and loss of firmness.

Sh-Heptapeptide-18 is typically found in serums, moisturisers, and targeted treatments. It works well alongside other peptides, antioxidants, and hydrating ingredients. Apply to clean skin morning or evening, or as directed by the product instructions. Peptides tend to be stable in leave-on formulations but may degrade in products exposed to heat or sunlight, so store products in a cool place and avoid excessive sun exposure after opening.

Peptides are generally well-tolerated by most skin types, including sensitive skin, as they are unlikely to trigger allergic reactions. Those with a known sensitivity to any ingredient in the formulation should perform a patch test first.