Sh-Oligopeptide-1

Sh-Oligopeptide-1 is a synthetic peptide — a short chain of amino acids — designed to mimic epidermal growth factor (EGF), a naturally occurring protein involved in skin repair and renewal. It functions as a skin conditioning agent, helping to support the skin's structural integrity and moisture retention.This ingredient is used in a relatively small proportion of skincare formulations (roughly 0.6% of products) and is typically incorporated at concentrations ranging from 2% to 99%, depending on the product type and intended use.

Helps with Anti-Ageing. For the Look of Scars

Sh-Oligopeptide-1 is thought to work by signalling to skin cells in a manner similar to natural growth factors. When applied topically, it may encourage the skin to strengthen its barrier function — the outer layer responsible for holding in moisture and keeping out irritants — and support the hydration of the stratum corneum (the skin's outermost layer).The exact mechanisms remain incompletely understood, and most evidence comes from formulations combining this peptide with other active ingredients, making it difficult to isolate its individual contribution.

Sh-Oligopeptide-1 is typically encountered in moisturisers, serums and treatment products formulated for sensitive or barrier-compromised skin. Apply according to the product instructions, usually once or twice daily. It pairs well with other hydrating and soothing ingredients such as hyaluronic acid and glycerol, and there are no known compatibility issues with common skincare actives.

Sh-Oligopeptide-1 is generally well-tolerated. As with any skincare ingredient, patch test if you have known sensitivities, and discontinue use if irritation occurs.