Peptides

Sh-Oligopeptide-9

INCI: SH-OLIGOPEPTIDE-9

Reviewed by Emma · Last updated 14 Aug 2026

A peptide ingredient that supports skin hydration and structural integrity

Best For Skin Types

All, Dry, Mature, Sensitive

Addresses

Dryness, Hydration, Fine lines, Barrier repair

Usage Frequency

Daily

What Is Sh-Oligopeptide-9?

Sh-Oligopeptide-9 is a short-chain peptide—a fragment of amino acids linked together—designed to mimic and support the skin's natural protein structures. Peptides are derived from the breakdown of larger proteins and are small enough to be absorbed by the skin, making them useful in topical formulations.

This ingredient functions primarily as a humectant, drawing moisture into the skin and helping it retain hydration. It also provides skin conditioning and protective properties, supporting the skin barrier's ability to maintain its structure and function.

How It Works

As a humectant, Sh-Oligopeptide-9 works by binding water molecules and drawing them into the outer layers of the skin. This increases hydration levels, which can improve the appearance of fine lines and give the skin a more refreshed look.

Beyond hydration, peptides are thought to signal to skin cells and support the maintenance of skin structure. By mimicking natural amino acid sequences, this ingredient may help reinforce the skin's barrier function and encourage a more resilient skin environment, though the degree of this effect varies depending on formulation and concentration.

Clinical Evidence & References

Research on skin ageing demonstrates that loss of dermal collagen and epidermal thinning are key features of aged skin. Peptide ingredients are included in skincare formulations on the basis that they can support skin hydration and protein function, though direct clinical evidence for Sh-Oligopeptide-9 specifically is limited in published literature.

The ingredient's humectant properties are well-established in cosmetic chemistry, and its inclusion in skincare products suggests efficacy in hydration support. However, more targeted research would be needed to confirm its specific effects on skin firmness, elasticity, or barrier repair at typical cosmetic concentrations.

How to Use

Sh-Oligopeptide-9 is typically found in serums, moisturisers, and hydrating treatments. It works well alongside other hydrating ingredients such as glycerol or hyaluronic acid. Apply to clean, damp skin for optimal hydration, or layer under a moisturiser to seal in benefits. It is generally stable in most formulations and can be used daily as part of a routine.

Safety & Precautions

Sh-Oligopeptide-9 is generally well-tolerated and has a low sensitising potential. As with any ingredient, patch testing is advisable for those with very sensitive or reactive skin.

Frequently Asked Questions

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