Best For Skin Types
All, Dry, Combination, Mature
Addresses
Usage Frequency
Daily
What Is Sh-Oligopeptide-78?
Sh-Oligopeptide-78 is a synthetic peptide—a short chain of amino acids—designed to function as both a conditioning agent and mild surfactant. Peptides are valued in skincare for their ability to interact with the skin's structural proteins and signalling pathways.
In formulations, this ingredient primarily works to improve texture and hydration, making products feel smoother and more pleasant on the skin. It is commonly found in hair and skincare products where conditioning properties are desired.
How It Works
As a peptide, Sh-Oligopeptide-78 is composed of amino acids that can interact with the skin's surface and potentially with deeper layers. Peptides are thought to support skin conditioning through their ability to bind water and smooth the skin's texture, creating a more refined appearance.
The ingredient also functions as a mild surfactant, meaning it can help blend oil and water-based components in formulations, improving product consistency and performance.
Clinical Evidence & References
Research on skin ageing shows that age-related changes—including loss of dermal collagen and epidermal thinning—are central concerns in skincare. Peptides in general have been studied for their potential role in supporting skin structure, though specific clinical evidence for Sh-Oligopeptide-78 is limited in published literature.
The ingredient is primarily used for its conditioning and textural benefits rather than for targeted clinical claims. If you are considering products containing this peptide for specific skin concerns such as fine lines or barrier support, it is worth viewing it as a supporting ingredient rather than a primary active.
How to Use
Sh-Oligopeptide-78 is typically incorporated into leave-on formulations such as serums, moisturisers, and conditioners. It works well as part of a broader skincare routine and does not require special application techniques. Use as directed by the product formulation.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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Sh-Oligopeptide-14
A peptide that conditions skin and supports its natural moisture retention
sh-Oligopeptide-2
Also known as Insulin-like growth factor 1 (IGF-1) | Stimulates cell proliferation and skin-comforting
Sh-Oligopeptide-4
A peptide fragment that supports skin conditioning and structural integrity
Sh-Oligopeptide-9
A peptide ingredient that supports skin hydration and structural integrity
Sh-Pentapeptide-12 Sp
A peptide that may help regulate skin inflammation and neural signalling
Sh-Pentapeptide-19
A peptide that supports skin's natural conditioning and structural integrity
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