Best For Skin Types
All, Dry, Mature
Addresses
Usage Frequency
Daily
What Is Sh-Oligopeptide-14?
Sh-Oligopeptide-14 is a short-chain peptide — a fragment of amino acids — designed to interact with skin's natural processes. Peptides are among the smallest protein-derived ingredients used in skincare, which theoretically allows them to penetrate the outer layers of skin more readily than larger proteins.
This particular peptide functions primarily as a skin conditioner, helping to improve how skin feels and behaves. It is included in formulations to support skin's hydration and overall condition, rather than to trigger dramatic structural changes.
How It Works
Peptides work by signalling to skin cells or by forming a conditioning film on the skin's surface. Sh-Oligopeptide-14 is believed to condition skin through both mechanisms — helping to smooth the skin's surface and supporting the skin's ability to hold onto water.
The precise molecular interactions are not extensively documented in public research, but the general theory is that short peptides can penetrate the stratum corneum (outer layer) and communicate with living skin cells to reinforce hydration and skin health.
Clinical Evidence & References
Published clinical data specifically on Sh-Oligopeptide-14 is limited. However, peptides as a category have shown modest benefits for skin hydration and appearance in several studies, particularly when used in formulations with other conditioning agents.
The evidence for peptides generally suggests they work best as part of a broader skincare routine rather than as standalone solutions. Results tend to be incremental and observable over consistent use, rather than dramatic.
How to Use
Use this ingredient as part of your regular routine, typically in serums, moisturisers, or treatment products. For best results, apply to clean skin and layer with other hydrating or nourishing products. Peptide-containing products are generally non-irritating, so they can be used daily by most people.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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Sh-Oligopeptide-1 Alanyl Sr-Spider Oligopeptide-1
A peptide derivative designed to support skin's natural protective barrier
Sh-Oligopeptide-10
A peptide fragment that supports skin conditioning and structural integrity
Sh-Oligopeptide-102 Sp
A peptide that may help regulate skin's inflammatory and sensory responses
sh-Oligopeptide-2
Also known as Insulin-like growth factor 1 (IGF-1) | Stimulates cell proliferation and skin-comforting
Sh-Oligopeptide-4
A peptide fragment that supports skin conditioning and structural integrity
Sh-Oligopeptide-78
A peptide-derived conditioning agent with dual benefits for hair and skin
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