Tranexamoyl Dipeptide-23

Tranexamoyl Dipeptide-23 is a peptide — a short chain of amino acids — that has been modified to include tranexamic acid, a compound with a history of use in medicine and skincare. This hybrid ingredient combines peptide technology with the lightening properties associated with tranexamic acid, creating a molecule intended to work on pigmentation at a cellular level.In skincare formulations, this ingredient is used primarily for its proposed ability to address uneven skin tone and hyperpigmentation. It sits within the broader category of peptide actives, which are increasingly popular in mo…

Tranexamoyl Dipeptide-23 is thought to influence melanin production — the pigment responsible for skin colour — by signalling to melanocytes (pigment-producing cells) to reduce their activity. The tranexamic acid component is believed to inhibit plasmin, an enzyme involved in triggering melanin synthesis, whilst the peptide structure may enhance skin penetration and stability.The result is a gradual evening of skin tone rather than immediate bleaching, which is why results typically develop over weeks of consistent use.

This ingredient works best as part of a consistent routine; expect to use it for at least 8–12 weeks before assessing results. Apply to clean, dry skin as directed by your product instructions, typically once or twice daily. Pair it with diligent sun protection (SPF 30 or above) every day, as UV exposure can counteract pigmentation-correcting efforts and trigger new spots.

Tranexamoyl Dipeptide-23 is generally considered well-tolerated and suitable for most skin types, including sensitive skin. No significant adverse effects have been widely reported, though patch testing is advisable if you have known sensitivities to peptides or tranexamic acid.