Urtica Dioica Extract
INCI: URTICA DIOICA EXTRACT
Reviewed by Kate · Last updated 14 Aug 2026
Also known as: Urtica Dioica (Nettle) Extract
Plant extract with antioxidant properties traditionally used to support skin and scalp health
Best For Skin Types
All, Sensitive, Oily
Addresses
Usage Frequency
Daily
EWG Safety Score
What Is Urtica Dioica Extract?
Urtica dioica extract comes from the common stinging nettle plant, which grows widely across temperate regions. The extract is prepared from the leaves and contains a range of polyphenolic compounds—naturally occurring plant chemicals with antioxidant properties. These compounds are what give nettle its long history of use in traditional medicine across many cultures.
In skincare, nettle extract functions primarily as a skin conditioner and soothing agent. It is also used in hair and scalp formulations for its conditioning and antidandruff properties, as well as for its mild astringent character.
How It Works
The antioxidant action of nettle extract stems from its polyphenolic content, which neutralises free radicals—unstable molecules that can damage skin cells and accelerate visible ageing. By reducing oxidative stress, these compounds may help protect fibroblasts (cells that produce collagen) from damage.
Research also suggests nettle extract may influence the enzyme 5-alpha-reductase in skin cells. This mechanism has been studied in relation to androgenic skin concerns, though evidence remains preliminary and primarily in-vitro. The soothing and conditioning effects are thought to work through multiple pathways, though the precise mechanisms in human skin are not fully characterised.
Clinical Evidence & References
Laboratory studies show that nettle extract protects human skin cells against oxidative stress and supports cell viability when exposed to harmful conditions. In-vitro research indicates the extract may inhibit 5-alpha-reductase activity in skin cells, which could theoretically have implications for androgenic skin conditions, though this has not been extensively studied in human skin or in clinical trials.
The ingredient has a long history of traditional use for skin and scalp health, but robust clinical evidence in humans is limited. Most supporting data comes from laboratory studies and preliminary research. Further investigation would help clarify its efficacy in real-world skincare applications.
Published Research
How to Use
Nettle extract appears in both skincare and haircare formulations, typically at low concentrations. In products, it works best as part of a broader formulation designed to address your specific concerns. For scalp health, consistent use over several weeks may be needed to assess effectiveness. As with any botanical ingredient, patch testing is sensible if you have particularly reactive skin.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizOther forms of Urtica Dioica Extract
These appear on ingredients lists under different names but are the same substance. Urtica Dioica Extract is the common form.
Related Ingredients
Urtica Dioica
A plant extract traditionally used to condition and support hair and scalp health
Urtica Dioica Root Extract
Root extract traditionally used to support skin condition and comfort
Hydrolyzed Nettle Leaf Extract
Plant-derived humectant and conditioning agent from nettle leaf
Urtica Dioica Leaf Extract
A plant extract with antioxidant and soothing properties, traditionally used in skincare
Urtica Dioica (Nettle) Extract
Plant extract with soothing properties
Tilia Cordata Extract
A plant extract traditionally used to soothe and condition the skin
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.