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iS Clinical Active Peel System Review

5 min read Updated Aug 10, 2026
iS Clinical Active Peel System in a lifestyle bathroom setting — Skintique review

The Verdict

A genuinely two-step system rather than a single exfoliating pad: Step 1's Salicylic Acid and Mixed Fruit Acid liquid does the resurfacing work, and Step 2's Copper Tripeptide-1 and Extremozyme® formula neutralises and hydrates straight afterwards, so skin isn't left stripped. It suits established actives users wanting an occasional at-home peel step rather than first-timers, since the tingling on Step 1 is a normal, expected part of how it works. As with any acid-based treatment, contact our team for advice before use if you're pregnant or breastfeeding.

iS Clinical Active Peel System | Two-Step Treatment | 15 Treatments

iS Clinical Active Peel System | Two-Step Treatment | 15 Treatments

£92.00

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The iS Clinical Active Peel System is a two-step, at-home exfoliating treatment: Step 1 is a Salicylic Acid and Mixed Fruit Acid liquid applied with biodegradable bamboo pads, Step 2 is a Copper Tripeptide-1 and Extremozyme® hydrating neutraliser. Used every other day or twice weekly, it's designed to help improve the appearance of skin tone and texture without the downtime of an in-clinic peel.

What is the iS Clinical Active Peel System?

It's a two-part kit that boxes up 15 treatments' worth of single-use bamboo pads, split into a Step 1 exfoliating liquid and a Step 2 hydrating neutraliser. According to the product listing, Step 1 is a thin, fast-absorbing liquid that produces a cool tingling sensation as it works — described as a normal sign the exfoliation has activated, and one that typically settles within a few minutes. Step 2 follows straight after, soaking the skin in a botanical, peptide-based formula that neutralises the Step 1 acids while delivering hydration. The system sits alongside iS Clinical's serums and creams as an occasional resurfacing step rather than a daily product, and the listing positions it as suitable for adults 18 and over, including sensitive and acne-prone skin.

Key ingredients

Step 1 and Step 2 are built around two exfoliating acids and two skin-conditioning actives, working in sequence rather than all at once:

  • Salicylic Acid — a BHA exfoliant in the Step 1 liquid, of particular relevance to oily, congested or blemish-prone skin.
  • Mixed Fruit Acids — AHA-type exfoliants working alongside the Salicylic Acid in Step 1; the listing doesn't break down which specific fruit acids are used or at what strength, so treat this as a blended AHA/BHA liquid rather than a single-acid peel. For how this family of acids generally works on skin, see our glycolic acid glossary entry.
  • Copper Tripeptide-1 — a copper peptide in the Step 2 formula, included to support the skin's own repair processes after exfoliation.
  • Extremozyme® Technology — iS Clinical's proprietary blend of extremophile-derived plant enzymes, included in Step 2 to help protect skin against environmental stressors; this is a branded ingredient complex rather than a single named compound, so we can't link it to a specific glossary entry.

Quick facts

FormatTwo-step at-home peel system, 15 treatments per box
Pad typeBiodegradable bamboo pads, single-use per treatment
Step 1 activesSalicylic Acid, Mixed Fruit Acids
Step 2 activesCopper Tripeptide-1, Extremozyme® Technology
SensationCool tingling on Step 1, settling within a few minutes
FrequencyEvery other day, or twice weekly
Tagged skin typesAll skin types, including sensitive and acne-prone skin
Suitable forAdults aged 18 and over

How to use

  1. Cleanse skin as normal and pat dry before starting.
  2. Sweep the Step 1 pad evenly over the face, avoiding the eye area, and leave the liquid to work — a cool tingling sensation is expected here.
  3. Follow immediately with the Step 2 pad, applied the same way, to neutralise the Step 1 acids and deliver hydration.
  4. Allow skin to absorb fully before applying the rest of your routine, and use sun protection the following day as standard practice after any exfoliating treatment.
  5. Use every other day or twice weekly rather than daily — this is a treatment step, not a daily-use product.

Who it's for

  • Established iS Clinical or actives users wanting an occasional at-home peel step between facials or professional treatments
  • Those dealing with uneven skin tone or texture who want a two-step exfoliate-then-hydrate routine rather than a leave-on acid product
  • Oily, congested or blemish-prone skin, given the Salicylic Acid content

Who should skip it

  • First-time actives users — start with a single, lower-strength exfoliant before introducing a combined AHA/BHA peel system
  • Anyone currently using other exfoliating acids, retinoids or in-clinic peels without leaving room to avoid over-exfoliating
  • Very reactive, broken or post-procedure skin — our Pro-Heal Serum Advance review and Hydra Cool Serum review cover gentler options built for compromised skin

Where it sits on price

The Active Peel System sits within iS Clinical's standard treatment-kit price band. iS Clinical isn't on Skintique's MAP-restricted brand list, but prices do move, so check the product page directly for the current figure rather than relying on a number here.

Pregnancy and breastfeeding

If you're pregnant or breastfeeding, please contact our team for advice before use.

FAQs

How often should I use the iS Clinical Active Peel System?

The listing recommends every other day or twice weekly. It's a treatment step rather than a daily product, so build up frequency gradually and watch how your skin responds.

What's actually in the iS Clinical Active Peel System?

Step 1 contains Salicylic Acid and Mixed Fruit Acids as the exfoliating actives. Step 2 contains Copper Tripeptide-1 and iS Clinical's proprietary Extremozyme® Technology to neutralise and hydrate afterwards.

Is the iS Clinical Active Peel System safe to use during pregnancy?

If you're pregnant or breastfeeding, please contact our team for advice before use.

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