Best For Skin Types
All
Addresses
Usage Frequency
Daily
What Is Caffeoyl Sh-Heptapeptide-13?
Caffeoyl Sh-Heptapeptide-13 is a synthetic peptide that combines a caffeic acid moiety (derived from natural sources like coffee and polyphenol-rich plants) with a seven-amino acid peptide chain. Peptides are short chains of amino acids that can penetrate the skin's outer layers and communicate with skin cells to trigger specific responses.
This ingredient functions as an antioxidant and skin protectant, working to neutralise free radicals and support the skin's natural defence mechanisms against environmental stress.
Benefits for Your Skin
How It Works
The caffeic acid component provides direct antioxidant activity by donating electrons to unstable free radicals, effectively neutralising them before they can damage skin cells. This helps prevent oxidative stress, which accelerates visible signs of ageing and weakens skin barrier function.
The peptide chain allows this active compound to penetrate more effectively into the skin and may also trigger cellular signalling pathways that enhance the skin's own protective mechanisms.
Clinical Evidence & References
Research into peptide safety in cosmetics indicates that caffeoyl-peptide compounds are generally well-tolerated and can be safely incorporated into skincare formulations. Caffeic acid itself has demonstrated tyrosinase-inhibiting properties in laboratory studies, which suggests potential benefits for even skin tone, though dedicated human studies on this specific peptide are limited.
The evidence supports its use as an antioxidant protective ingredient, though further clinical research in human subjects would strengthen confidence in specific efficacy claims for visible skin outcomes.
How to Use
Caffeoyl Sh-Heptapeptide-13 is typically found in serums, moisturisers, and targeted treatments. It pairs well with other antioxidants (such as vitamin C or niacinamide) and can be used daily as part of a morning or evening routine. Apply to clean skin before moisturiser for optimal absorption.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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Caffeoyl Pentapeptide-20
A peptide-derived antioxidant that helps protect skin from environmental stress
Caffeoyl Pentapeptide-4
A peptide derivative that supports skin conditioning and structural integrity
Caffeoyl Sh-Decapeptide-9
A peptide-derived ingredient that conditions skin and may support even skin tone
Caffeoyl Sh-Octapeptide-4
A peptide-derived antioxidant that may help protect skin and support even tone
Caffeoyl Tripeptide-1
A peptide antioxidant that helps protect skin from environmental stress
Caffeoyl Tripeptide-34
A peptide derivative with potential to support skin conditioning and pigmentation control
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