Peptides

Methionyl R-Salmon Oligopeptide-1 Sh-Polypeptide-51

INCI: METHIONYL R-SALMON OLIGOPEPTIDE-1 SH-POLYPEPTIDE-51

Reviewed by Rosie · Last updated 2 Jun 2026

Also known as: Methionyl R-salmon Oligopeptide-1 Sh-polypeptide-51

A salmon-derived peptide blend with antioxidant and skin-protective properties

Best For Skin Types

All, Sensitive, Mature

Addresses

Fine lines, Environmental stressors, Barrier repair

Usage Frequency

Daily

What Is Methionyl R-Salmon Oligopeptide-1 Sh-Polypeptide-51?

Methionyl R-Salmon Oligopeptide-1 Sh-Polypeptide-51 is a peptide derived from salmon. Peptides are short chains of amino acids, and this particular ingredient combines two peptide structures to create a molecule designed to support skin health.

In formulations, it functions primarily as an antioxidant and skin protectant, helping to neutralise free radicals and support the skin's natural defence mechanisms against environmental stressors.

Benefits for Your Skin

How It Works

The ingredient works through its antioxidant capacity, which allows it to donate electrons to unstable free radical molecules, thereby stabilising them and preventing them from damaging skin cells. Free radicals are unstable molecules generated by UV exposure, pollution, and natural metabolic processes.

By reducing free radical activity, the ingredient may help protect skin from cumulative oxidative damage, which is implicated in visible ageing and skin barrier compromise.

Clinical Evidence & References

Published clinical data on this specific ingredient combination is limited. Most evidence for salmon peptides in skincare comes from in vitro studies and ingredient supplier data rather than rigorous human trials.

The antioxidant and protective properties are plausible based on peptide chemistry, but direct evidence of efficacy in human skin remains sparse. If you are considering this ingredient for a specific concern, it may be worth assessing it as part of a broader skincare approach rather than as a standalone solution.

How to Use

This ingredient is typically incorporated into serums, moisturisers, and treatment products at low concentrations. It is generally compatible with most other skincare actives, though as with any new product, introduce it gradually and observe your skin's response before combining it with multiple treatment ingredients.

Safety & Precautions

Generally well-tolerated in skincare formulations. Those with fish allergies should check product labelling, as salmon-derived ingredients may pose a risk.

Frequently Asked Questions

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