Peptides

Myristoyl Hexapeptide-23

INCI: MYRISTOYL HEXAPEPTIDE-23

Reviewed by Emma · Last updated 14 Aug 2026

Also known as: Myristoyl Hexapeptide-23

A peptide derivative designed to support skin conditioning and maintain skin comfort

Best For Skin Types

All, Dry, Sensitive, Mature

Addresses

Dryness, Barrier repair, Sensitivity

Usage Frequency

Daily

What Is Myristoyl Hexapeptide-23?

Myristoyl Hexapeptide-23 is a synthetic peptide—a short chain of amino acids—combined with a myristoyl fatty acid component. This structure is designed to enhance how the ingredient penetrates and behaves within the skin, allowing it to function effectively as a skin conditioning agent.

In skincare formulations, this ingredient works to support the skin's natural moisture retention and overall condition, though the specific mechanisms remain an area of ongoing research.

How It Works

The peptide component works by signalling to skin cells, whilst the fatty acid attachment helps it penetrate the outer layers of skin effectively. This combination allows the ingredient to interact with the skin's conditioning mechanisms rather than simply sitting on the surface.

The exact molecular targets remain incompletely characterised in published literature, which is common with newer synthetic peptide derivatives.

Clinical Evidence & References

Research on Myristoyl Hexapeptide-23 specifically is limited in the published scientific literature. The ingredient appears in skincare products primarily as a skin conditioning agent, though robust clinical data supporting particular efficacy claims are not widely available.

Given the peptide structure and fatty acid modification, there is theoretical support for skin barrier and hydration benefits, but this remains to be substantiated by large-scale human studies.

How to Use

This ingredient is typically found in moisturisers, serums and conditioning treatments. It works well alongside other hydrating or barrier-supporting ingredients. There is no specific timing requirement; use it as part of your regular skincare routine according to product instructions.

Safety & Precautions

Myristoyl Hexapeptide-23 is generally well-tolerated in skincare formulations. Those with known sensitivities to peptides should patch test before broader use.

Frequently Asked Questions

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