Myristoyl Pentapeptide-4

Myristoyl Pentapeptide-4 is a synthetic peptide—a short chain of amino acids attached to a fatty acid (myristic acid). Peptides are fragments of proteins, and when formulated into skincare, they can interact with the skin barrier and support its natural functions.This ingredient is primarily used as a skin conditioning agent, helping to improve the feel and hydration status of the skin surface.

Myristoyl Pentapeptide-4 works through its dual structure: the peptide portion can interact with skin proteins, whilst the fatty acid component helps it remain on the skin surface. This combination allows it to condition the skin and help maintain hydration.The mechanism is largely cosmetic rather than deeply transformative—it conditions the outer layers of skin rather than triggering significant biochemical changes in deeper tissue.

Myristoyl Pentapeptide-4 is typically found in serums, moisturisers and treatment products. It works well alongside other hydrating ingredients and can be layered with vitamin C, hyaluronic acid or niacinamide. No special precautions are needed—apply as directed by the product formulation, usually morning and evening.

Myristoyl Pentapeptide-4 is generally well-tolerated and considered safe for cosmetic use. Peptide ingredients rarely cause sensitivity, though those with known peptide sensitivities should patch test first.