Peptides

Myristoyl Pentapeptide-11

INCI: MYRISTOYL PENTAPEPTIDE-11

Reviewed by Rosie · Last updated 14 Aug 2026

Also known as: Myristoyl Pentapeptide-11

A peptide derivative designed to support skin conditioning and maintain skin texture

Best For Skin Types

All, Mature, Dry

Addresses

Texture, Skin conditioning

Usage Frequency

Daily

What Is Myristoyl Pentapeptide-11?

Myristoyl Pentapeptide-11 is a peptide compound created by attaching a myristoyl fatty acid chain to a five-amino-acid peptide sequence. This conjugation enhances the ingredient's ability to penetrate the skin and remain stable within formulations.

In skincare products, it functions primarily as a skin conditioning agent, meaning it helps to maintain or improve the texture and feel of the skin surface. Peptides in general are valued in skincare because they are small enough to potentially interact with skin cells, though the extent of their effects varies depending on their specific structure and molecular weight.

How It Works

The myristoyl chain acts as a delivery vehicle, helping the peptide penetrate the outer layers of skin more effectively than the peptide alone might. Once in the skin, peptides can interact with skin cells to support conditioning effects, though the precise mechanisms for this particular ingredient remain incompletely characterised.

The five-amino-acid sequence is designed to be small and stable enough to survive formulation conditions while remaining functional at the skin surface or within the epidermis.

Clinical Evidence & References

Research on myristoyl pentapeptide-11 specifically is limited in published literature. The ingredient is classified as a skin conditioning agent based on its chemical composition and behaviour in formulations, but robust clinical studies demonstrating measurable improvements in skin appearance or function have not been widely reported.

General peptide research suggests that peptides can support skin texture and appearance when present in adequate concentrations, though results are often modest and individual responses vary. The addition of a fatty acid chain to peptides does improve their skin penetration profile, which theoretically enhances their efficacy, but this has not been extensively validated for this particular ingredient in human studies.

How to Use

Myristoyl Pentapeptide-11 is typically found in leave-on products such as serums, moisturisers and treatments. For best results, use consistently as part of your routine. It pairs well with other skin conditioning agents and can be combined with most other skincare ingredients, though as with any new addition to your routine, introduce it gradually to monitor tolerance.

Safety & Precautions

Myristoyl Pentapeptide-11 is generally well-tolerated and has a low risk profile in cosmetic applications. Those with sensitivity to peptides or fatty acid derivatives should patch-test first.

Frequently Asked Questions

From the Clinic

Not sure what your skin actually needs?

Two minutes, a few questions, and we’ll point you at what matters — no guesswork.

Take the skin quiz

Learn More About Skincare Ingredients

Explore our comprehensive ingredient glossary to understand what's in your products.

Browse All Ingredients

Authorised Stockist

Official UK retailer

Tracked Delivery

Free UK shipping over £50

5 Star Rating

Trusted by thousands

Expert Advice

Free consultations