Best For Skin Types
All, Dry, Combination, Mature
Addresses
Usage Frequency
Daily
What Is Myristoyl Pentapeptide-16?
Myristoyl Pentapeptide-16 is a peptide—a short chain of amino acids—that has been chemically modified with a myristoyl (fatty acid) component. This modification allows the peptide to penetrate the skin more effectively and remain stable within formulations.
In skincare, it functions primarily as a skin conditioning agent, working to support the skin's texture and overall appearance. Peptides in general are thought to communicate with skin cells and may help reinforce the skin's structure.
How It Works
As a peptide, Myristoyl Pentapeptide-16 is thought to interact with skin cells to provide signalling cues that support healthy skin behaviour. The addition of the myristoyl fatty acid chain makes it lipophilic—fat-soluble—which enhances its ability to cross the skin barrier and remain in the skin rather than washing away.
Once in the skin, it may help condition the stratum corneum (the outermost layer) and support the skin's natural moisturising factors, contributing to improved texture and a more refined appearance.
Clinical Evidence & References
Evidence specifically on Myristoyl Pentapeptide-16 in skincare is limited. Most research on peptides in general suggests they have a conditioning and potentially supportive role in skin health, though the depth of clinical support varies widely depending on the specific peptide and study design.
The research base for this particular peptide is not robust enough to make strong claims about efficacy. It is best regarded as a skin conditioning ingredient with theoretical benefits based on peptide science, rather than one with established clinical proof of significant anti-ageing or transformative effects.
How to Use
Myristoyl Pentapeptide-16 is typically used in serums, moisturisers and treatment products at concentrations that allow it to remain stable. There is no requirement to use it in isolation; it works well within layered routines alongside other conditioning and hydrating ingredients. Apply to clean skin as part of your regular skincare regimen.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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