Palmitoyl Sh-Oligopeptide-79

Palmitoyl Sh-Oligopeptide-79 is a peptide—a short chain of amino acids—that has been modified with a palmitoyl group (a fatty acid derivative). This modification helps the peptide penetrate the skin more effectively and interact with cellular structures. In skincare formulations, it is primarily used for its conditioning and structural support properties.Peptides are commonly used in skincare because they can signal to skin cells to maintain or strengthen their function. This particular peptide is found in a small proportion of skincare products and is typically used in formulations targeti…

Peptides work by communicating with skin cells. When applied topically, they can be recognised by cell receptors, which may trigger signalling pathways involved in maintaining skin structure and firmness. The palmitoyl modification makes this particular peptide more likely to penetrate the outer layers of skin and reach these cellular receptors.By supporting the skin's existing structural proteins, this ingredient aims to help maintain the skin's appearance and resilience over time, though the depth of penetration and efficacy of topical peptides remains an area of ongoing research.

This ingredient is typically found in serums, moisturisers and conditioning products. Use as directed on the product label. It works best as part of a consistent skincare routine and is generally compatible with other active ingredients, though it is sensible to introduce it gradually if you have reactive skin.

Peptides are generally well-tolerated by most skin types. As with any skincare ingredient, patch test before full application if you have a history of sensitivity.