Phosphatidylserine

Phosphatidylserine is a naturally occurring phospholipid—a type of fat molecule—found in all human cell membranes. In skincare formulations, it functions as an emulsion stabiliser, helping to bind water and oil-based ingredients together, whilst also providing skin conditioning benefits.As a structural component of cells, phosphatidylserine plays a role in cell signalling and membrane integrity. When applied topically, it helps support the skin's natural barrier function and can improve the texture and feel of skincare products.

Phosphatidylserine mimics the natural lipids that exist in the outer layers of skin. When applied topically, it integrates with the skin's own lipid matrix, reinforcing barrier function and reducing transepidermal water loss. This helps the skin retain moisture more effectively.As a formulation ingredient, phosphatidylserine stabilises emulsions by positioning itself at the interface between water and oil phases, preventing separation and ensuring product consistency over time.

Phosphatidylserine is typically found in serums, moisturisers and barrier-repair products at low concentrations. Since it works best as part of a complete formulation, use it alongside other hydrating or barrier-supporting ingredients. Apply to clean skin and follow with any additional treatments suited to your routine.

Phosphatidylserine is generally well-tolerated and considered safe for topical use. No significant adverse effects have been reported in cosmetic applications.