Sh-Polypeptide-18

Sh-Polypeptide-18 is a short-chain peptide—a fragment of amino acids linked together—designed to function as a skin conditioning agent in topical formulations. Peptides are naturally present in skin as building blocks of proteins like collagen, which provides structure and elasticity.This ingredient works primarily to improve skin texture and hydration by helping to condition the outer layers of skin. It does not penetrate deeply into the dermis, but rather works at the surface to support the skin's appearance and feel.

Peptides like Sh-Polypeptide-18 work by depositing on the skin's surface, where they form a conditioning film. This film helps to smooth the outer layer of skin and can improve how water is retained in the stratum corneum—the outermost barrier.Unlike larger collagen molecules, peptides are smaller and may have limited ability to penetrate beyond the epidermis. Their primary benefit is therefore cosmetic conditioning rather than deep structural reformation, though they may contribute to the overall appearance of firmness and elasticity when used consistently.

Sh-Polypeptide-18 is typically found in serums, moisturisers, and treatment products at concentrations that optimise skin conditioning without irritation. It works well alongside other hydrating and supporting ingredients. Apply to clean skin, morning and evening, as part of your regular routine for cumulative conditioning benefits.

Peptides are generally well-tolerated by most skin types. As with all skincare ingredients, discontinue use if signs of irritation develop, and perform a patch test if you have very sensitive skin.