Best For Skin Types
All, Dry, Mature, Sensitive
Addresses
Usage Frequency
Daily
What Is Sh-Polypeptide-31?
Sh-Polypeptide-31 is a peptide—a short chain of amino acids—used in skincare formulations primarily for skin conditioning purposes. Peptides function as signalling molecules in the skin, communicating with cells to support various physiological processes. This particular peptide is designed to help maintain skin condition and support the skin's structural proteins.
As a conditioning agent, it works to improve the texture and feel of the skin, helping formulations deliver a smoother, more refined appearance over time with regular use.
How It Works
Peptides like Sh-Polypeptide-31 are believed to communicate with skin cells through specific receptors, triggering cellular responses that support skin health and function. As amino acid chains, they can penetrate the outer layers of the skin and influence how cells behave and maintain themselves.
By supporting the skin's natural conditioning processes, this peptide helps maintain moisture retention and skin firmness, which become increasingly important as skin ages and loses collagen and elasticity naturally.
Clinical Evidence & References
Research on skin ageing shows that loss of dermal collagen and thinning of both the epidermis and dermis are primary drivers of visible ageing signs including wrinkles and laxity. Peptides are theoretically well-positioned to support skin structure, as they can communicate with cells to encourage maintenance of proteins like collagen.
However, specific clinical data on Sh-Polypeptide-31 is limited in publicly available literature. General peptide research supports their role in skin conditioning, though individual peptides vary in efficacy. More targeted studies would help clarify this ingredient's specific contribution to skin health outcomes.
How to Use
Sh-Polypeptide-31 is typically found in serums, moisturisers, and targeted treatments. Apply to clean skin morning and evening as part of your regular routine. It works well in layered routines alongside other conditioning and hydrating ingredients, and is generally compatible with most active skincare ingredients.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
Sh-Polypeptide-2
A peptide that conditions and supports the skin's structural integrity
Sh-Polypeptide-22
A peptide designed to support skin structure and hydration as part of an anti-ageing routine
Sh-Polypeptide-3
A peptide that supports skin conditioning and structural integrity
Sh-Polypeptide-4
A peptide fragment that supports skin antioxidant defences and conditioning
Sh-Polypeptide-45
A peptide that supports skin conditioning and structural integrity
Sh-Polypeptide-47
A peptide that supports skin's natural conditioning and structural integrity
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.