Sh-Polypeptide-45

Sh-Polypeptide-45 is a peptide—a short chain of amino acids—formulated to function as a skin conditioning agent. Peptides are naturally occurring compounds found throughout the body, where they play roles in skin structure and function. In skincare formulations, this ingredient is included to help maintain and support the skin's natural condition.As a skin conditioning agent, Sh-Polypeptide-45 works at the surface and upper layers of the skin, helping to improve how skin looks and feels. Peptides in general have been studied for their role in supporting skin barrier health and firmness, tho…

Peptides function by signalling to skin cells and supporting the maintenance of structural proteins. Sh-Polypeptide-45 operates as a humectant and conditioning agent, drawing moisture into the skin and creating a smoother surface texture.The ingredient works primarily at the skin's surface and outer layers, where it can help optimise hydration and improve how skin appears to the eye. This conditioning action contributes to a more supple, resilient complexion over time.

Sh-Polypeptide-45 is typically found in serums, moisturisers, and treatment products. Apply to clean skin as directed by the product instructions, usually once or twice daily. Peptide-containing products can be layered with other skincare actives, though as with any new ingredient, introduce it gradually to monitor how your skin responds.

Peptides are generally well-tolerated across most skin types. As with any ingredient, discontinue use if irritation or sensitisation occurs.