SkinCeuticals A.G.E. Interrupter Advanced | Anti-Ageing Corrective Cre – Skintique Retail

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SkinCeuticals A.G.E. Interrupter Advanced | Anti-Ageing Corrective Cream | 48ml

The next-generation anti-wrinkle cream

Skin Types - All Skin Types, Dry, Mature, Normal, Combination, and Sensitive

£157.50 £175.00

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More Information

Additional Product Information

Size: 48ml

Texture: Rich, creamy formulation with luxurious satin finish

Skin Type Suitability: Dry, normal, combination, and sensitive skin; all Fitzpatrick types I-VI

Clinical Testing: 12-week clinical study on 77 participants demonstrating significant wrinkle reduction across five facial zones; physician-tested to complement RF microneedling treatments

Free-From Claims: Formulated without parabens, drying alcohol, or dyes

Packaging: Protective jar with hygienic spatula included to minimize contamination

Special Notes

Research Foundation: Backed by over 15 years of glycation research and expertise from SkinCeuticals' dermatological laboratories

Colour Variation: Due to the high concentration of naturally derived flavonoids (blueberry and pomegranate extracts), the cream's colour may vary slightly between batches; this natural variation does not affect product efficacy

Clinical Validation: Physician-tested to complement RF microneedling treatments, delivering 3x better lifting results in 12 weeks when used in conjunction with professional procedures

Professional Recommendation: Trusted by dermatologists and medical aesthetic professionals worldwide for at-home corrective treatment

Application Efficiency: Only a small amount is required per application due to the concentrated, high-performance formulation

Directions

How To Use

Application: Massage a thin, even layer onto cleansed face, neck, and chest. Only a small amount is needed due to the concentrated formulation. Gently massage until fully absorbed.

Frequency: Twice daily for optimal results — morning and evening

Timing:

Morning Regimen: Apply after cleansing and toning. Follow with a SkinCeuticals vitamin C antioxidant serum (such as C E Ferulic), then apply A.G.E. Interrupter Advanced, and finish with a broad-spectrum sunscreen.

Evening Regimen: Apply after cleansing and toning. If using retinol, apply retinol first, allow to absorb, then follow with A.G.E. Interrupter Advanced as your final treatment step.

Layering: Works synergistically with SkinCeuticals serums including H.A. Intensifier, Resveratrol B E, and vitamin C formulations. For comprehensive anti-aging benefits, our experts recommend pairing with A.G.E. Advanced Eye around the delicate eye area.

Expert Tips: For enhanced results, incorporate this treatment as part of a comprehensive professional skincare regimen. Patients undergoing RF microneedling or other collagen-stimulating procedures should apply consistently both before and after treatments to maximize lifting and firming benefits. Always apply sunscreen during the day as the final step, as consistent UV protection is essential to prevent further glycation and oxidative damage.

Ingredients

Full Ingredients List

Aqua/Water, Hydroxypropyl Tetrahydropyrantriol, Glycerin, Propylene Glycol, Stearic Acid, Butyrospermum Parkii Butter/Shea Butter, Hydroxyethylpiperazine Ethane Sulfonic Acid, Palmitic Acid, Pentylene Glycol, Oleyl Alcohol, Arachidyl Alcohol, Myristyl Myristate, Panthenol, Niacinamide, Dimethicone, Isononyl Isononanoate, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Glyceryl Stearate, Candelilla Cera/Candelilla Wax, Behenyl Alcohol, PEG-100 Stearate, Sodium Polyacrylate, Pentaerythrityl Tetraisostearate, 4-T-Butylcyclohexanol, Arachidyl Glucoside, Caprylyl Glycol, Xanthan Gum, Chlorphenesin, Myristic Acid, Caprylic/Capric Triglyceride, Glycyrrhetinic Acid, Parfum/Fragrance, Sorbitol, Vaccinium Myrtillus Fruit Extract, Potassium Hydroxide, Adenosine, Citric Acid, Punica Granatum Fruit Extract, Limonene, Coumarin, Linalool, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Please note: Formulations are updated periodically by manufacturers without notice. Therefore, the ingredient lists on this website may differ from the product packaging depending on the time and country of purchase. Please refer to your product packaging for accurate ingredient lists. A patch test before use must be carried out for suitability.

FAQ

FAQ

Q: How does A.G.E. Interrupter Advanced differ from the original A.G.E. Interrupter formulation?

A: A.G.E. Interrupter Advanced represents a significant evolution in anti-glycation science. The advanced formulation contains 18% concentrated Proxylane (compared to 30% in the original, but in a more concentrated, bioavailable form representing 20% more efficacy), 4.25% wild fruit flavonoid blend (12.5% more than the original), and introduces glycyrrhetinic acid for enhanced anti-inflammatory and radiance-boosting benefits. The texture has been refined to provide a richer, more luxurious satin finish whilst the formula is now free from parabens and drying alcohol. Clinical testing demonstrates superior efficacy in reducing five distinct wrinkle types and improving skin density.

Q: Can I use A.G.E. Interrupter Advanced if I have sensitive skin?

A: Yes, this formulation has been physician-tested and clinically validated for use on sensitive skin across all Fitzpatrick skin types (I-VI). The formula is free from parabens and drying alcohol, ingredients that can sometimes trigger sensitivity. However, the product does contain fragrance components that may cause reactions in highly sensitive individuals. We recommend conducting a patch test before full facial application. If you have specific concerns or a history of contact dermatitis, speak to our skincare experts for personalized guidance on incorporating this treatment into your regimen.

Q: When can I expect to see visible results from using A.G.E. Interrupter Advanced?

A: Based on clinical studies, many users report improvements in skin texture, hydration, and radiance within the first 4 weeks of consistent twice-daily use. Significant wrinkle reduction and improvements in skin firmness typically become apparent by week 8-12. The 12-week clinical study demonstrated measurable improvements including 14% reduction in global fine lines, 11% reduction in forehead wrinkles and nasolabial folds, and enhanced skin density. For optimal results, commit to consistent application twice daily as part of a comprehensive professional skincare regimen including daily SPF protection. Results are progressive and cumulative with continued use.

Q: Can I use this treatment alongside retinol or vitamin C serums?

A: Absolutely. A.G.E. Interrupter Advanced has been specifically formulated to work synergistically with other professional skincare actives. In the morning, apply after your SkinCeuticals vitamin C antioxidant serum (such as C E Ferulic or Phloretin CF) and before sunscreen. In the evening, if using retinol, apply retinol first, allow it to absorb completely, then follow with A.G.E. Interrupter Advanced. This treatment's rich, nourishing texture helps buffer any potential dryness from retinol whilst delivering complementary anti-aging benefits. Our experts can provide personalized layering guidance to optimize your complete regimen.

Q: Why does the cream's colour sometimes vary between purchases?

A: The natural colour variation is due to the high concentration of wild fruit flavonoids derived from blueberry and pomegranate extracts. These naturally occurring botanical compounds can vary slightly in pigmentation depending on harvest conditions and seasonal factors. This is actually an indicator of the formula's authenticity and high concentration of active botanical ingredients. Rest assured that colour variation does not affect the product's efficacy, stability, or safety — the clinical performance remains consistent regardless of slight colour differences.

Q: Is this treatment suitable for use around the eyes?

A: Whilst A.G.E. Interrupter Advanced is formulated for the face, neck, and chest, SkinCeuticals offers A.G.E. Advanced Eye specifically formulated for the delicate eye area. The eye cream addresses similar glycation-related concerns including crow's feet, dark circles, and loss of firmness with a formulation optimized for the thinner, more sensitive eye zone. Our experts recommend using both products in tandem for comprehensive anti-aging benefits across the entire face — A.G.E. Advanced Eye around the orbital area and A.G.E. Interrupter Advanced on the rest of the face, neck, and chest.

Delivery

Free UK delivery is available for all orders over £50.

Orders under £50 are subject to a delivery fee of £4.95.

All orders are sent via a tracked service and you will be emailed a tracking number once dispatched.

Express delivery is available for some brands at an extra cost with a cut off time of 2pm and subject to stock.

Express delivery and high-value orders over £100 are sent with a Tracked 24 signed for delivery.

Your order will be dispatched within 1-2 working days and is estimated to be delivered after dispatch within 2-4 working days for standard shipping and 1-3 working days on an express service. Subject to stock availablity.

Cut-off for standard shipping orders is 3:30 pm (2:00pm Fridays) subject to stock.

Orders placed after 2pm on Fridays will not be dispatched until the following Monday subject to the above schedule.

Please see our full Shipping policy
Please see our full Returns policy.

Key Benefits

  • Targets Complete Glycation Process: Addresses the multi-phase biological process where excess sugars bind to collagen and elastin, helping to reverse glycation-related aging by up to 33%
  • Reduces Five Wrinkle Types: Clinically shown to improve forehead wrinkles, nasolabial folds, marionette lines, glabellar wrinkles, and crow's feet — the five wrinkle types most frequently targeted in aesthetic procedures
  • Restores Skin Density and Firmness: Significantly increases total skin density and filaggrin protein levels, helping to restore the structural integrity compromised by collagen decline
  • Delivers 24-Hour Hydration: Provides continuous moisture throughout the day in a rich, satin-finish texture whilst supporting the skin's natural moisture barrier
  • Complements Professional Treatments: Physician-tested to enhance results of RF microneedling and other skin-tightening procedures, achieving 3x better lifting outcomes when used as part of an integrated regimen

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SkinCeuticals A.G.E. Interrupter Advanced | 48ml-Targeted Treatment-Skintique Retail
SkinCeuticals

SkinCeuticals A.G.E. Interrupter Advanced | Anti-Ageing Corrective Cream | 48ml

£157.50 £175.00

Product Overview - SkinCeuticals A.G.E. Interrupter Advanced | Anti-Ageing Corrective Cream | 48ml

SkinCeuticals A.G.E. Interrupter Advanced is a next-generation corrective cream meticulously formulated to address visible aging impacted by glycation and collagen decline. Backed by over 15 years of clinical glycation research, this advanced anti-wrinkle treatment targets the multi-phase biological process where excess sugars bind to collagen and elastin, creating damaging advanced glycation end-products (A.G.E.s) that lead to wrinkles, loss of firmness, and dullness.

This potent corrective formula combines 18% Concentrated Proxylane (representing a significant 20% increase from the original formulation), 4.25% Wild Fruit Flavonoid Blend featuring antioxidant-rich blueberry and pomegranate extracts, and 0.1% Glycyrrhetinic Acid derived from liquorice root. Together, these clinically-proven ingredients work synergistically to help reverse glycation-related aging by up to 33%, whilst delivering luxurious 24-hour hydration in a rich, satin-finish texture. Suitable for dry, normal, combination, and sensitive skin types across all ages seeking to address moderate to advanced visible signs of aging.

Key Benefits at a Glance

Immediate Benefits:
Long-Term Benefits:

With consistent twice-daily use, this clinically-proven formulation delivers transformative improvements backed by rigorous testing. In a comprehensive 12-week clinical study involving 77 participants, A.G.E. Interrupter Advanced demonstrated remarkable efficacy in reducing five distinct wrinkle types frequently targeted in aesthetic procedures: achieving 14% reduction in global fine lines, 11% improvement in both forehead wrinkles and nasolabial folds, plus 7% reduction in marionette lines, glabellar wrinkles, and crow's feet.

Beyond wrinkle reduction, this advanced corrective cream significantly increases skin density and firmness whilst helping to restore the skin's structural integrity compromised by glycation. The formulation works to reverse visible collagen decline, addressing the root causes of aging rather than simply masking symptoms. Our experts particularly recommend this treatment for those seeking professional-grade results and complementary support for in-clinic procedures such as RF microneedling.

How Will It Feel on My Skin?

This next-generation corrective cream offers a rich, creamy texture that feels luxurious upon application yet absorbs beautifully without any greasy residue. The formula glides effortlessly across the skin, requiring only a small amount to cover the entire face, neck, and chest. Upon application, you'll experience an immediate sensation of nourishment and comfort, with the cream leaving a sophisticated satin finish that serves as an excellent base for makeup. The non-comedogenic formulation has been physician-tested for tolerance across all skin types, including sensitive skin, ensuring comfortable daily use without irritation.

Who Is It Suitable For?

Why Choose A.G.E. Interrupter Advanced?

Backed by over 15 years of dedicated glycation research and extensive clinical testing, this breakthrough corrective cream represents the pinnacle of evidence-based anti-aging science. Clinically proven to help reverse glycation by up to 33% and physician-tested to complement professional treatments for enhanced lifting results, it addresses the complete glycation process rather than simply treating surface symptoms. Our experts recommend this professional-grade formulation for clients seeking transformative, clinically-validated results supported by published research and dermatologist endorsement.

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