Niacinamide Thioctate

Niacinamide thioctate is a hybrid ingredient that combines niacinamide (vitamin B3) with thioctic acid (also known as alpha-lipoic acid), a potent antioxidant. This combination aims to deliver the skin-conditioning benefits of niacinamide alongside additional antioxidant protection.The ingredient functions as both a skin conditioner and antioxidant, meaning it can help support skin barrier function whilst simultaneously defending against oxidative stress from environmental factors such as UV exposure and pollution.

Niacinamide thioctate delivers two complementary mechanisms. The niacinamide portion supports skin barrier function and cellular health, whilst the thioctic acid component acts as an antioxidant by neutralising free radicals that can contribute to visible skin ageing and irritation.By combining these two components, the ingredient may offer broader antioxidant and conditioning support than either ingredient alone, though evidence specific to this combination remains limited.

Niacinamide thioctate is typically used as part of a serum or treatment product. Apply to clean skin as directed by the product instructions. It can generally be layered with other skincare ingredients, though it is often found in antioxidant-focused formulations designed to be used in the morning to provide daytime protection.

Niacinamide is generally well-tolerated across skin types. Those with sensitivity to thioctic acid or niacinamide should perform a patch test first. As with any new ingredient, introduce gradually to monitor for any adverse reactions.