Best For Skin Types
All, Mature, Dry
Addresses
Usage Frequency
Daily
What Is Rh-Polypeptide-11?
Rh-Polypeptide-11 is a synthetic peptide — a chain of amino acids designed to mimic natural protein structures found in skin. Peptides function as signalling molecules and conditioning agents, helping to support the skin's barrier and overall appearance.
In skincare formulations, this ingredient works primarily as a skin conditioner, helping to improve texture and maintain skin suppleness. It is typically used in modest concentrations within moisturisers, serums, and treatment products.
How It Works
Peptides like Rh-Polypeptide-11 are thought to work through multiple mechanisms. They can form a conditioning film on the skin surface, improving hydration and tactile softness. At a deeper level, peptides may communicate with skin cells, potentially triggering responses that support collagen maintenance and skin resilience.
The ingredient is particularly relevant to ageing skin, where loss of structural proteins — especially collagen — contributes to visible changes. By providing amino acid-based support, peptides may help address some of the underlying causes of age-related skin changes.
Clinical Evidence & References
Research on skin ageing consistently demonstrates that both the epidermis and dermis undergo thinning with time, largely due to a decline in collagen and other structural proteins. Peptide-based ingredients are designed to address this loss through various pathways, though the evidence base for individual peptides varies considerably.
While the theoretical rationale for peptide use in skincare is sound, specific clinical data on Rh-Polypeptide-11 itself is limited in publicly available literature. General peptide research supports their role in skin conditioning and potential support for barrier function, but individual results depend on formulation, concentration, and skin type. As with many cosmetic peptides, robust comparative studies would strengthen the evidence base.
How to Use
Rh-Polypeptide-11 is typically found in serums, moisturisers, and treatment products designed for mature or condition-specific skin. It can generally be used daily as part of your regular routine, either morning or evening. Peptide products often work best when layered with complementary ingredients such as hydrators or antioxidants, and consistency of use will yield better results than occasional application.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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Retinoyl Tripeptide-1
A peptide compound combining retinoid activity with skin-conditioning benefits
Retinyl Palmitate/Carrot Polypeptide
A combination of retinoid and plant peptides designed to condition and support skin renewal
Rh-Polypeptide-1
A peptide that supports skin's structural integrity and protective functions
Rh-Polypeptide-111
A peptide derivative with potential structural support benefits for ageing skin
Rh-Polypeptide-22
A peptide that conditions skin and supports its structural integrity
Rh-Polypeptide-3
A peptide that supports skin structure and conditioning
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