Best For Skin Types
All, Mature, Dry
Addresses
Usage Frequency
Daily
What Is Rh-Polypeptide-3?
Rh-Polypeptide-3 is a synthetic peptide—a chain of amino acids designed to mimic natural protein structures found in skin. Peptides function as signalling molecules and structural support agents within skincare formulations, working to condition and support the skin's natural barrier.
This ingredient is classified as a skin conditioner, meaning it helps to improve the texture, feel, and overall condition of the skin surface rather than penetrating deeply into living tissue.
How It Works
Peptides work by signalling to skin cells and providing structural conditioning at the skin's surface. Rh-Polypeptide-3 is thought to support the skin's natural protein architecture, which naturally diminishes with age and environmental stress.
Rather than directly replacing lost collagen, this peptide functions as a conditioning agent—helping to optimise how the skin feels and behaves whilst supporting its natural barrier integrity.
Clinical Evidence & References
Research on peptides in skincare demonstrates that they can improve skin texture, hydration perception, and the appearance of fine lines through their conditioning and signalling properties. Skin aging involves progressive loss of collagen and thinning of both the epidermis and dermis, making structural support ingredients relevant to addressing these concerns.
However, specific clinical data on Rh-Polypeptide-3 itself is limited in published literature. The ingredient's benefits should be understood within the broader context of how peptides support skin structure and conditioning, rather than as a standalone anti-aging solution.
How to Use
Peptides like Rh-Polypeptide-3 are typically incorporated into serums, moisturisers, and treatment products. They work well layered with other conditioning and hydrating ingredients. There is no specific timing requirement; use as part of your regular skincare routine according to the product instructions.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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Rh-Polypeptide-11
A peptide that conditions and supports the skin's structural integrity
Rh-Polypeptide-111
A peptide derivative with potential structural support benefits for ageing skin
Rh-Polypeptide-22
A peptide that conditions skin and supports its structural integrity
Rh-Polypeptide-31
A peptide-derived ingredient that supports skin's natural defence mechanisms
Rice Rh-Polypeptide-45
A rice-derived peptide that conditions and protects the skin
Rice Sh-Oligopeptide-1
Synthetic peptide derived from rice | Designed to mimic growth factors in skin
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