Peptides

Rice Rh-Polypeptide-45

INCI: RICE RH-POLYPEPTIDE-45

Reviewed by Rosie · Last updated 2 Jun 2026

Also known as: Rice Rh-polypeptide-45

A rice-derived peptide that conditions and protects the skin

Best For Skin Types

All

Addresses

Fine lines, Sensitivity, Environmental protection

Usage Frequency

Daily

What Is Rice Rh-Polypeptide-45?

Rice Rh-Polypeptide-45 is a peptide derived from rice, a plant that has a long history of use in skincare. Peptides are short chains of amino acids that can interact with skin cells and support various skin functions.

In formulations, this ingredient is primarily used as a skin conditioner and protectant, helping to maintain skin's appearance and support its natural defences.

How It Works

Rice-derived peptides work by interacting with skin cells to support their natural functions. Peptides are recognised by the skin and may help strengthen skin's structural integrity and resilience.

Additionally, rice contains compounds with antioxidant properties that may help counteract oxidative stress—a process linked to skin ageing and environmental damage. This dual mechanism of conditioning and protection is why rice-based ingredients feature in skincare formulations.

Clinical Evidence & References

Rice and its components have been the subject of several studies examining their potential benefits for skin health. Research suggests that rice-derived ingredients possess antioxidant, anti-inflammatory, and photoprotective properties, and have been associated with improvements in skin appearance when used in cosmetic formulations.

However, specific clinical evidence for Rice Rh-Polypeptide-45 in isolation is limited. Most available research examines rice bran extracts or whole rice components rather than this particular peptide. Further targeted studies would help establish its efficacy more definitively.

How to Use

Rice Rh-Polypeptide-45 is typically found in serums, creams, and moisturisers. Use as directed in your chosen product. It works well alongside other skin conditioning and protective ingredients, and can be incorporated into both morning and evening routines.

Safety & Precautions

Rice-derived ingredients are generally well-tolerated by most skin types. No significant safety concerns have been identified, though those with rice allergies should exercise caution.

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