Rh-Polypeptide-111

Rh-Polypeptide-111 is a synthetic peptide — a short chain of amino acids — designed to support the skin's structural proteins. Peptides are widely used in skincare formulations because they can penetrate the outer layer of skin and communicate with cells to encourage supportive functions.This particular peptide is included in formulations primarily for its potential to address age-related changes in skin structure, though detailed functional data on this ingredient remains limited in publicly available research.

Peptides work by signalling to skin cells, particularly fibroblasts in the dermis, to maintain or increase production of structural proteins like collagen and elastin. As skin ages, both the epidermis and dermis naturally thin, and collagen production decreases — a process that contributes to wrinkles and loss of firmness.By introducing a peptide derivative, the theory is that skin cells receive a 'reminder' to continue producing these essential proteins, helping to slow or mitigate visible signs of ageing.

Peptide-containing products are generally well-tolerated as part of a daily skincare routine. Apply to clean, dry skin before moisturiser, or layer within your existing regimen. Consistency matters with peptides — they work best with regular use over several weeks. Combine with broad-spectrum SPF during the day, as sun exposure accelerates the collagen breakdown that peptides aim to prevent.

Peptides are generally well-tolerated and suitable for most skin types, including sensitive skin. As with any new ingredient, apply a small amount first to check for individual sensitivity.