Sh-Polypeptide-7

Sh-Polypeptide-7 is a peptide—a short chain of amino acids—designed to mimic or support natural skin proteins. Peptides are increasingly used in skincare because they can interact with skin cells to influence various biological processes, including barrier function and sebum production.This ingredient is classified as both antiseborrhoeic (helping to regulate excess oil) and skin-protecting, suggesting it may help normalise sebum levels whilst supporting the skin's natural defences against environmental stressors.

Peptides work by communicating with skin cells, signalling them to behave in specific ways. Sh-Polypeptide-7 appears to influence sebaceous glands—the structures that produce sebum—potentially normalising their output rather than over-producing or under-producing oil.Additionally, peptides can support the skin's barrier layer, which comprises lipids, proteins, and moisture. A stronger barrier means better protection against external irritants and reduced water loss, both essential for healthy skin function.

Sh-Polypeptide-7 is typically found in serums, moisturisers, and targeted treatments. Apply to clean skin before heavier creams or oils to allow maximum contact with skin cells. It can be used daily as part of a routine, though it's sensible to introduce it gradually if you have sensitive skin and observe any changes in oil production or barrier comfort over 2-4 weeks.

Peptides are generally well-tolerated and considered safe for most skin types. As with any ingredient, discontinue use if you experience irritation, and perform a patch test if you have particularly reactive skin.