Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-6
INCI: NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-POLYPEPTIDE-6
Reviewed by Emma · Last updated 2 Jun 2026
Also known as: Nicotiana Benthamiana Hexapeptide-40 Sh-polypeptide-6
A plant-derived peptide designed to support skin conditioning and firmness
Best For Skin Types
All
Addresses
Usage Frequency
Daily
What Is Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-6?
Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-6 is a peptide derived from Nicotiana benthamiana, a plant species related to tobacco. It is a short-chain protein fragment (hexapeptide) combined with a larger polypeptide structure, designed to function as a skin conditioning agent.
Peptides in skincare are valued for their potential to support skin structure and firmness. This particular ingredient is included in formulations to help maintain skin condition and support the appearance of elasticity.
How It Works
Peptides function by signalling to skin cells to support natural maintenance processes. This hexapeptide-polypeptide combination is designed to interact with the skin's surface and deeper layers to reinforce conditioning and firmness.
The ingredient works as part of a formulation's overall strategy to support skin condition rather than as a standalone active ingredient.
Clinical Evidence & References
Published research specifically on this ingredient is limited. The evidence base relies largely on the established role of peptides in skincare and the ingredient supplier's technical data supporting its conditioning function.
Like many plant-derived peptides, it is included in products based on mechanism and traditional use patterns rather than extensive clinical trial data. Its effects are modest and best evaluated as part of a complete skincare routine rather than in isolation.
How to Use
Use this ingredient as directed within your formulated product. Peptide-containing products are typically suitable for daily use as part of your morning or evening routine. Consistency of use supports better results over time.
Safety & Precautions
Frequently Asked Questions
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