Best For Skin Types
All, Dry, Mature
Addresses
Usage Frequency
Daily
What Is Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2?
Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2 is a peptide derived from the Nicotiana benthamiana plant (a relative of tobacco). This ingredient is created through biotechnology, where the plant is used as a production system to generate specific peptide sequences that may benefit skin.
Peptides are short chains of amino acids. In skincare, they are used because they can penetrate the outer layers of skin and may influence cellular processes. This particular peptide is included in formulations intended to address visible signs of ageing and support skin hydration.
Benefits for Your Skin
How It Works
This peptide is thought to work by interacting with skin cells in a way that may stimulate the production or activity of fibroblasts—the cells responsible for producing collagen and elastin. If this mechanism holds true in topical application, it could theoretically support skin structure and resilience over time.
However, the evidence for topical efficacy in humans remains limited. Most research has focused on the production method and laboratory-based cellular responses rather than proven effects on living human skin.
Clinical Evidence & References
Research exists on the production and characterisation of this peptide in plant systems, and laboratory studies suggest potential activity in fibroblast-related pathways. However, robust clinical evidence demonstrating visible anti-ageing benefits in human skin is currently limited.
The ingredient appears in skincare products marketed for anti-ageing and hydration, but independent human studies validating these claims are not widely available. More research would strengthen confidence in its efficacy at typical cosmetic concentrations.
Published Research
How to Use
This ingredient is typically found in serums, creams and moisturisers as part of a broader formulation. For best results, use consistently as part of your daily routine. Like most peptide-containing products, results develop gradually over weeks of regular use rather than immediately.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-86
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Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-9
A plant-derived peptide with potential applications in addressing skin ageing
Nicotiana Benthamiana Rh-Oligopeptide-1
A plant-derived peptide designed to support skin's natural protective functions
Nicotinoyl Dipeptide-22
A niacinamide derivative designed to help even skin tone and reduce pigmentation
Nicotinoyl Dipeptide-23
A peptide derivative that supports skin conditioning and resilience
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